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6.1%First documentBreast Cancer: Who Is At The Risk? - Oncquest Blog- Your Health GuideOpen original ↗
Second documentStatus of Breast Cancer and Related Tests - Oncquest Blog- Your Health GuideOpen original ↗
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ARE SOME PEOPLE MORE LIKELY THAN OTHERS TO HAVE A BRCAGENE MUTATION?
Women with a mutation in the BRCA1 & 2 genes are at increased risk for cancer of the breast and ovary. These risks may vary. Women with an altered BRCA1 & 2 genes have a 50 to 85% risk of developing breast cancer by age 70. Risk for cancer of the ovary is 40 to 60% by age 85. A woman with cancer in one breast has a higher risk of developing cancer in the other breast. 25 to 30% of those with a BRCA1 change may get a second breast cancer within ten years after their first incidence of breast cancer.
GENETIC TESTS
Most inherited cases of breast cancer are associated with two abnormal genes: BRCA1 (Breast Cancer Gene 1) or BRCA2 (Breast Cancer Gene 2). Women who inherit a mutation or abnormal change in either of these genes have a much higher than the average lifetime risk of developing breast and ovarian cancer. Women with an abnormal BRCA1 or BRCA2 gene have about a 60%-85% risk of being diagnosed with breast cancer during their lifetimes (compared to 12-13% for women overall). (Source: National Cancer Institute)